The induced Pluripotent Stem Cells (iPSC) Core was created in 2011 to accelerate stem cell research in the NHLBI by providing investigators consultation, technical services and training in human pluripotent stem cell technology. The major services that the Core currently provides are derivation, maintenance and characterization of human iPSCs. The Core also provides control iPSC lines and validated iPSC culture reagents. In addition to providing services and consultations to researchers from various disciplines, the Core staff is developing human iPSC gene-editing technologies, establishing lineage-specific differentiation protocols and collaborates with investigators in specific projects. Research conducted by the Core seeks to better understand the mechanisms underlying pluripotent stem cell self-renewal and differentiation to optimize culture conditions and operating procedures.
Jizhong Zou, Ph.D.